Needs cosmetics and updating
Botulinum toxin is used to treat a number of disorders characterized by overactive muscle movement, including post-stroke spasticity, post-spinal cord injury spasticity, spasms of the head and neck, Strabismus is caused by imbalances in the actions of muscles that rotate the eyes, and can sometimes be relieved by weakening a muscle that pulls too strongly, or pulls against one that has been weakened by disease or trauma.
Muscles weakened by toxin injection recover from paralysis after several months, so it might seem that injection would then need to be repeated.
In January 2014, botulinum toxin was approved by UK's Medicines and Healthcare Products Regulatory Agency (MHRA) for treatment of restricted ankle motion due to lower limb spasticity associated with stroke in adults.
On July 29, 2016, Food and Drug Administration (FDA), of the United States of America approved abobotulinumtoxin A for injection for the treatment of lower limb spasticity in pediatric patients two years of age and older.
Namely, they warned that the toxin can spread to areas distant from the site of injection and paralyze unintended muscle groups, especially when used for treating muscle spasticity in children treated for cerebral palsy.The toxin is also used commercially in medicine, cosmetics and research.Botulinum is the most acutely lethal toxin known, with an estimated human median lethal dose (LD Botulinum toxin types A and B are used in medicine to treat various muscle spasms and diseases characterized by overactive muscle.Botulism can be difficult to diagnose, as it may appear similar to diseases such as Guillain–Barré syndrome, myasthenia gravis, and stroke.Other tests, such as brain scan and spinal fluid examination, may help to rule out other causes.